Steroid pharmacology ppt

Approximately 70% of all human genes are expressed in colorectal cancer, with just over 1% of having increased expression in colorectal cancer compared to other forms of cancer. [40] Some genes are oncogenes : they are overexpressed in colorectal cancer. For example, genes encoding the proteins KRAS , RAF , and PI3K , which normally stimulate the cell to divide in response to growth factors, can acquire mutations that result in over-activation of cell proliferation. The chronological order of mutations is sometimes important. If a previous APC mutation occurred, a primary KRAS mutation often progresses to cancer rather than a self-limiting hyperplastic or borderline lesion. [41] PTEN , a tumor suppressor, normally inhibits PI3K, but can sometimes become mutated and deactivated. [38]

  1. Encyclopædia Britannica articles are written in a neutral objective tone for a general audience.
  2. You may find it helpful to search within the site to see how similar or related subjects are covered.
  3. Any text you add should be original, not copied from other sources.
  4. At the bottom of the article, feel free to list any sources that support your changes, so that we can fully understand their context. (Internet URLs are the best.)

Steroid pharmacology ppt

steroid pharmacology ppt

Media:

steroid pharmacology pptsteroid pharmacology pptsteroid pharmacology pptsteroid pharmacology pptsteroid pharmacology ppt